The invention is directed toward a malleable bone putty and a flowable gel
composition for application to a bone defect site to promote new bone
growth at the site which comprises a new bone growth inducing compound of
demineralized lyophilized allograft bone powder. The bone powder has a
particle size ranging from about 100 to about 850 microns and is mixed in
a high molecular weight hydrogel carrier, the hydrogel component of the
carrier ranging from about 0.3 to 3.0% of the composition and having a
molecular weight of about at least 10,000 Daltons. The composition
contains about 25% to about 40% bone powder and can be additionally
provided with BMP's and a sodium phosphate buffer.