The present invention provides a method for the part purification of
fibrinogen from milk, the method comprising the transfer of protease
enzyme which is present in the milk, into the whey phase with the removal
or partition if fibrinogen into another phase of the milk. The present
invention also provides a method for obtaining fibrinogen from a fluid,
the method comprising: a) contacting the fluid with a hydrophobic
interaction chromatography resin under conditions where the fibrinogen
binds to the resin; and b) removing the bound protein by means of
elution.