A patient transfer device includes a top sheet inclined in a head end portion such that a patient's torso is elevated with respect to the feet. The mattress may include relatively narrow chambers in an intermediate portion for increased strength and stability. The mattress may also include a leg separator in a foot end portion, preferably tapered and including one or more inflatable chambers. The mattress may also include a pump mounted directly to the mattress. The transfer device may include a torso and head support accessory having independently inflatable torso and head chambers and inlet and exhaust tubes connected to each chamber. A distribution manifold includes valves connected to each of the inlet and exhaust tubes for controlled inflation and deflation of the chambers. The device may include a control unit connected to the manifold and mountable to an intubation tube for actuation by a user's thumb.