A disk drive includes a rotatable data storage disk having a plurality of radially distributed tracks, and where radial pitch between at least some of the tracks varies across the disk. A head is configured to read/write data on the tracks. An actuator is configured to position the head relative to the disk. A controller is configured to respond to a host read/write command identifying a track address on the disk by determining a corresponding shifted radial location on the disk that is radially offset from an actual location of the addressed track by a distance that at least partially compensates for the radial pitch variation between at least some of the tracks on the disk. Corresponding methods are disclosed for positioning a head that is adjacent to a rotatable disk in a disk drive so as to at least partially compensate for radial pitch variation between at least some of the tracks on the disk.