Compound corresponding to the general formula (I): ##STR00001## in which A=N or CR.sub.2; R.sub.2=H, F, OH, CN, CF.sub.3, C.sub.1-6-alkyl, C.sub.1-6-alkoxy; n=2 or 3 and m=2 when A=N; n=1, 2 or 3 and m=1 or 2 when A=CR.sub.2; B=covalent bond or C.sub.1-8-alkylene; R.sub.1=optionally substituted heteroaryl; R.sub.3=CHR.sub.4CONHR.sub.5; R.sub.4=H or C.sub.1-6-alkyl; R.sub.5=H, C.sub.1-6-alkyl, C.sub.3-7-cycloalkyl, C.sub.3-7-cycloalkyl-C.sub.1 C.sub.6-alkylene; in the form of a base, an acid-addition salt, a hydrate or a solvate. Therapeutic uses thereof.

 
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> Bafilomycin-like metabolite from a novel micromonospora species

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