A clock generation system for generating a first-, a second-, and a third-reference frequency clocks having respective frequencies having predetermined ratios to the reference frequency of a reference clock, using PL circuits in such a way that the clocks have sufficient S/N ratios in spite of the S/N ratio limitation by the noise floor. A first reference frequency clock is supplied to a first PLL circuit to generate an intermediate-frequency clock having an intermediate frequency having a predetermined ratio to the reference clock. The intermediate-frequency clock is supplied to a second and a third PLL circuits to generate a second and a third reference frequency clocks having frequencies respectively having a second and a third ratios to the intermediate frequency, respectively.