The presently claimed invention provides methods and kits for amplifying a
target sequence from within a nucleic acid population. The presently
claimed invention provides selection probes which are complementary to at
least a portion of said target sequence and mechanisms for adding a probe
sequence to the 3' end of a target sequence that is hybridized to a
selection probe. The added 3' probe sequence and a probe sequence added
at the 5' end of the target by adaptor ligation allow for selective
amplification of the target sequence.