System and method for elimination of close-in interferers through feedback. A preferred embodiment comprises an interferer predictor (for example, interferer predictor 840) coupled to a digital output of a direct RF radio receiver (for example, radio receiver 800). The interferer predictor predicts the presence of interferers and feeds the information back to a sampling unit (for example, sampling unit 805) through a feedback circuit (for example, feedback unit 845) through the use of charge sharing. The interferers are then eliminated in the sampling unit. Additionally, the number and placement of zeroes in a filter in the sampling unit is increased and changed through the implementation of arbitrary-coefficient finite impulse response filters.