A pair of eyeglasses with lens fastening arrangement includes a frame having two sets of one or more through holes formed on an outer top and/or bottom edge of each of a pair of openings. The through holes communicate with grooves of the openings. A pair of lenses each includes one or more projections formed on an outer top and/or a bottom edge of each lens. The projection is adapted to lockingly engage with the through hole with peripheral edges of the lenses being inserted into the grooves of the openings of the frame when the lenses are firmly fitted in the openings of the frame. Thereby, loosening of the lenses by bending temples of the eyeglasses is substantially impossible.