The invention relates to new compounds, 3-phenylpropionic acid derivatives
of formula (I) wherein W represents COOH group or its bioisosters, or
--COO--C.sub.1 C.sub.4-alkyl group; Y represents NH, N--C.sub.1
C.sub.10-alkyl, O, or S; X represents O, S, NH, N--C.sub.1
C.sub.10-alkyl, N-aryl, NSO.sub.2--C.sub.1 C.sub.10-alkyl,
N--SO.sub.2-aryl, or N--SO.sub.2-heteroaryl; R.sub.1 to R.sub.8 each
independently represents hydrogen atom or a substituent defined in the
description; A is as defined in the description; n represents an integer
from 0 to 4, inclusive; and pharmaceutically acceptable salts thereof.
The compounds are the ligands of PPAR-gamma receptor and are useful as
medicaments ##STR00001##