The invention provides diagnostic procedures wherein the presence or
absence of a cell-proliferating disorder, e.g., a breast cancer, may be
determined. The imaging agents of the invention include alpha-fetoprotein
hydrophilic analogs which have been determined to target cancers, e.g.,
breast cancer, and are also anti-cell proliferating in nature. These
modulators contain amino acid structures which are arranged as a
hydrophilic analog of an alpha-fetoprotein. The modulator may be a
peptide; a peptidomimetic; or may be in the form of a pharmaceutically
acceptable scaffold, such as a polycyclic hydrocarbon to which is
attached the necessary amino acid structures. The imaging agents of the
invention further comprise an imaging moiety that allows for the imaging
of the area targeted by the imaging agent.