The present invention provides for an antisense oligonucleotide having the
sequence 5'GCTCGGCGCCGCCATTTCCAG3'. The invention also provides for an
antisense oligonucleotide having the sequence 5'GTCAGCGGCCATCAGCTT3'. The
present invention further provides for a method for treating a
neurodegenerative disorder in a subject which comprises administering to
the subject a compound in an amount effective to inhibit neuronal cell
death and thus treat the neurodegenerative disorder in the subject, which
compound comprises the oligonucleotide 5'GCTCGGCGCCGCCATTTCCAG3' and a
delivery agent. The present invention provides for a method of inhibiting
trophic factor withdrawal mediated death of a cell which comprises
contacting the cell with an amount of the oligonucleotide
5'GCTCGGCGCCGCCATTTCCAG3' effective to inhibit death of the cell.