The invention discloses a new clause of a five membered heterocylic ring
compounds of general formula I ##STR00001## and its pharmaceutically or
cosmetically acceptable salts, wherein R1, R2, R3, R4, R5, A, B, X and Y
are as defined in the specification. The invention also discloses a
process for preparation of these compound and their therapeutic and
cosmetic applications particularly in the management of aging related and
diabetic vascular complications. The compounds in question act by triple
action of an AGE (Advanced Glycation Endproducts) breaker, AGE inhibitor
and free radical scavenger which make them most suitable in different
therapeutic and cosmetic applications. The invention also discloses
pharmaceuticals and cosmetic compositions comprising these compounds and
method of treatment of diseases caused by accumulation of AGE and/or free
radicals in the body cells.