The invention provides an isolated or purified peptide that binds at least
one plasma protein. In one embodiment, the isolated or purified peptide
binds to fibrinogen, comprises no more than 10 amino acids, and comprises
an amino acid sequence Xaa.sub.1-Xaa.sub.2-Xaa.sub.3-Xaa.sub.4-Xaa.sub.5,
an amino acid sequence Gly-Xaa.sub.6-Arg-Xaa.sub.7, or an amino acid
sequence selected from specific amino acid sequences provided herein.
Alternatively, the isolated or purified protein binds to .alpha.l
proteinase inhibitor and/or a protein complex comprising Apo-A1
lipoprotein and paraoxonase. The peptide comprises no more than 10 amino
acids and comprises an amino acid sequence
Xaa.sub.8-Xaa.sub.8-Xaa.sub.1-His-Xaa.sub.1-Xaa.sub.3, and amino acid
sequence His-Xaa.sub.8-Xaa.sub.9-Xaa.sub.1-Xaa.sub.10-Xaa.sub.2, or an
amino acid sequence selected from specific amino acid sequences provided
herein. In addition, the invention provides isolated or purified peptide
that binds to von Willebrand Factor. The peptide comprises an amino acid
sequence Xaa.sub.4-Xaa.sub.5-Xaa.sub.5, an amino acid sequence
Tyr-Leu-Xaa.sub.11-Xaa.sub.4-Xaa.sub.12-Thr, or an amino acid sequence
selected from specific amino acid sequences provided herein.