The invention relates to novel bispecific antibodies and their use in
tumor therapy. The novel antibodies have the ability to bind to ErbB
receptors, preferably ErbB1 receptors, which are overexpressed on many
cancer tissues. Since the different specificities of the antigen-binding
sites are directed to different epitopes within the binding domain of
same or different ErbB receptors, these antibodies are more effective
with respect to inhibition and down-regulation of the ErbB receptor and
the corresponding signaling cascade.