A suspension of vector particles (PV) based on polyamino acids and have a
mean hydrodynamic diameter between 30 and 120 nm, and an insulin load
factor of from 5 to 25% of associated insulin volume relative to the
polyamino acid volume forming the vector particles. The polyamino acids
are double-block polymers containing hydrophilic and hydrophobic
monomers. The suspension may be prepared by copolymerizing N-carboxy
anhydrides of hydrophobic monomers and precursors of hydrophilic
monomers, in the presence of N-methyl pyrrolidone and methanol. The
copolymer is optionally neutralized, subjected to dialysis, concentrated
and water is eliminated to produce a solid powder, which can be suspended
in a liquid to produce the colloidal suspension. Active principles such
as insulin or vaccines are associated with the carrier particles to
prepare special pharmaceutical products.