The present application describes modulators of CCR3 of formula (Ia) and
(Ib): ##STR00001## or pharmaceutically acceptable salt forms thereof,
wherein Z, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.5',
R.sup.6, a, b, c, d, and u are as defined herein. In addition, methods of
treating and preventing inflammatory diseases such as asthma and allergic
diseases, as well as autoimmune pathologies such as rheumatoid arthritis
and atherosclerosis using said modulators are disclosed.