In one aspect, the invention provides a process for the preparation of
compounds of Formula I ##STR00001## wherein R.sub.1 is --CN, --OP,
alkyl, aryl or heteroaryl; wherein P represents any suitable protecting
group; and R.sub.2 is alkyl or aryl; by reacting a compound of Formula II
##STR00002## wherein R.sub.1 is --CN, --OP, alkyl, aryl or
heteroaryl; wherein P represents any suitable protecting group; and
R.sub.2 is alkyl or aryl; with a reducing agent (e.g. sodium borohydride)
in the presence of a metal halid (e.g. CeCl.sub.3) or a metal alkoxid
(e.g. Ti(OiPr).sub.4).