Methods and apparatus are disclosed for performing lookup operations using associative memories, including, but not limited to modifying search keys within an associative memory based on modification mappings, forcing a no-hit condition in response to a highest-priority matching entry including a force no-hit indication, selecting among various sets or banks of associative memory entries in determining a lookup result, and detecting and propagating error conditions. In one implementation, each block retrieves a modification mapping from a local memory and modifies a received search key based on the mapping and received modification data. In one implementation, each of the associative memory entries includes a field for indicating that a successful match on the entry should or should not force a no-hit result. In one implementation, an indication of which associative memory blocks or sets of entries to use in a particular lookup operation is retrieved from a memory.