A cultivated tomato plant having a genome including an introgression derived from a green-fruited tomato, the green-fruited tomato being characterized by fruits having a brix value above 5 brix units, the introgression including a portion of chromosome 9 of the green-fruited tomato, the portion extending telomerically to a point so as to exclude from the portion an allele of the green-fruited tomato being responsible for an undesired trait selected from the group consisting of higher percent green fruit yield and longer internodes characterizing the green-fruited tomato as is compared to the cultivated tomato plant, the introgression inherently increasing by at least 6% a brix value characterizing fruits of the cultivated tomato plant as is compared to a nearly isogenic tomato plant lacking the introgression.

 
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> Methods of treatment using specific binding agents of human angiopoietin-2

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