Systems and methods are disclosed herein for the non-intrusive inspection and/or verification of cargo. In an exemplary embodiment, an elemental signature is determined at a first point in a supply chain and transmitted to a second point in the supply chain. When the goods arrive at the second point, the elemental signature of the goods may be measured and verified against the original elemental signature. In another embodiment, an elemental signature may be measured to verify the origin or identity of the goods. In some embodiments such elemental signatures are inherent to the shipped goods and/or their packaging. In other embodiments, elemental signatures are applied to the shipment as tag materials.