An electronic control system is provided to permit one-person loading and unloading of a vessel from a trailer. The control moves the vessel using bow, stern and fore/aft thrusters that are supplied by the boat manufacturer. Operator inputs to the system controller of the instant invention consist of one or more multi-axis joysticks and a multi-axis foot pedal that are mounted onboard the vessel and a hand-held remote control that permits owner control of the vessel while standing on shore. For one-person unloading and loading of the vessel from and to a trailer, the owner may, using the remote control, drive the vessel off of the trailer to a remote location in the water, park and have the vessel maintain its position with respect to GPS satellites, and call for the vessel to return to the launch point using location data that was previously recorded by the system control.