A method and computer-readable medium are provided for previewing and performing actions on attachments to electronic mail messages. A first window pane is displayed that includes a list of e-mail messages and information identifying any attachments to the e-mail messages. When an attachment is selected, a preview is generated for the attachment and displayed in a second window pane adjacent to the first window pane. Actions that may be performed on the attachment are also identified and made available. One provided action includes the ability to quickly generate a reply message to the e-mail that includes a changed version of the original attachment.