A prosthetic sock configured to accommodate a transtibial amputee's residuum volume reductions which occur over time and are greater distally than proximally. It is also applicable to other amputee limbs and other levels of amputation of the leg and arm. The sock provides better compensation for the increased distal volume shrinkage and it reduces discomfort from localized loading on the stump by providing a knitted thickness that is greater distally and then tapers to a lesser proximal knitted thickness. A transtibial amputee's residuum is more sensitive to pressure over the tibial bone and this sock also provides a reduced local thickness over the tibial crest area which decreases the localized pressure in this region. Since the sock accommodates the loss of tissue volume in the distal end of the prosthetic socket, it thereby provides improved stump stability inside the prosthetic socket and improves amputee control and stability in walking.