The invention features a method of playing a card game using a deck of numbered cards. Each player is dealt a predetermined number of cards, so that each player possesses a card set, or "hand" of cards. The remaining cards form a draw pile, and one card from the draw pile is turned face up to start a separate discard pile. The object of the game is for each player to remove cards from its card set by discarding a card that is either a multiple or a divisor of a card shown on the top of a common discard pile.