Systems, methodologies, media, and other embodiments associated with electrocardiogram electrode characterization and compensation are described. One exemplary system embodiment includes a characterization logic configured to generate signals designed to facilitate characterizing an electrocardiogram electrode. The characterization logic may also be configured to analyze signals produced in response to introducing the signals into a subject. The example system may also include a compensation logic configured to determine whether an electrode is performing in a desired manner and to selectively compensate for electrode performance.