X-ray imaging systems and methods are provided that use temporal digital signal processing for reducing noise and for obtaining multiple images simultaneously. An x-ray imaging system can include an x-ray source adapted to generate a pulsed x-ray beam having a predetermined frequency and apply the pulsed x-ray beam to an object to be imaged. An x-ray detector can be adapted to detect x-ray radiation from the object and generate temporal data based on the x-ray radiation. A temporal data analyzer can be adapted to apply a temporal signal process to the temporal data to remove at least a portion of the temporal data having a different frequency than the predetermined frequency.