The invention discloses a new clause of a five membered heterocylic ring
compounds of general formula I and its pharmaceutically or cosmetically
acceptable salts, wherein R1, R2, R3, R4, R5, A, B, X and Y are as
defined in the specification. The invention also discloses a process for
preparation of these compound and their therapeutic and cosmetic
applications particularly in the management of aging related and diabetic
vascular complications. The compounds in question act by triple action of
an AGE (Advanced Glycation Endproducts) breaker, AGE inhibitor and free
radical scavenger which make them most suitable in different therapeutic
and cosmetic applications. The invention also discloses pharmaceuticals
and cosmetic compositions comprising these compounds and method of
treatment of diseases caused by accumulation of AGE and/or free radicals
in the body cells.