The present invention concerns a plunging jet bioreactor (1) comprising a
mechanism (4), (5) adapted in use to form culture fluid into a hollow
flow stream and to introduce into the hollow of the flow stream an
oxygen-containing gas. In some embodiments the mechanism comprises
concentrically arranged outer (4) and inner tubes (5) wherein the inner
tube is in flow communication with the culture fluid container whereby
the culture fluid flows over the inner tube to form the hollow flow
stream into which the oxygen from the inner tube is introduced.