A method of analyzing an ultrasound image of a target volume having therein at least two types of substances is disclosed. The method comprises: dividing a region-of-interest of the image to a set of mini-segments. The method further comprises, for each mini-segment, calculating at least two representative intensity values, respectively representing the at least two types of substances. The method further comprises applying attenuation corrections to each representative intensity value of at least a subset of the set of mini-segments, so as to map the region-of-interest according to the at least two types of substances.