Systems and methods for repairing annulus defects include at least one blocking member positionable in or adjacent to the annulus defect, at least one attachment portion for securing the blocking member to adjacent tissue, and instruments for placing and engaging the blocking member in and/or adjacent to the annulus defect. The blocking member extends at least partially across the annulus defect for repair of the defect and/or retention of nucleus material, one or more implants, bio-compatible materials or device, and/or other objects positioned in the disc space.