An animal ear treatment solution is formulated with an organosilane polymer antimicrobial in a concentration of approximately 0.25% to approximately 3.0% by weight, a surfactant or homeopathic active ingredient, and an optional holistic antiseptic such as green tea oil or eucalyptus oil. The solution is formulated to have a pH of about 10 but less than 12. Weekly application of the solution within an animal's ear canal allows the organosilane polymer antimicrobial to attach to tissue within the ear canal, forming a mechanical barrier against growth of bacteria on such tissue. The holistic antiseptic, if present within the solution, acts to destroy bacteria within the ear canal.