Efficient provision of hemodynamic benefits and therapy for patients
suffering from intraventricular conduction delays or conduction blockage.
By effectively measuring conduction delay or block (e.g., left bundle
branch block or "LBBB") and enhancing delivery of a novel form of left
ventricle-only cardiac resynchronization therapy. Accordingly, a single
LV fusion pacing stimulus is triggered from an atrial event (e.g.,
intrinsic or evoked depolarization). The triggering event can emanate
from the right atrium (RA) or the left atrium (LA). The single LV fusion
pacing stimulus is delivered prior to the intrinsic depolarization of the
RV--upon expiration of a "LEPARS interval"--thus efficiently providing
intraventricular electromechanical synchrony by fusion. During variations
in heart rate the operating AV interval (herein A-LVp interval) is varied
while the LEPARS interval is substantially essentially constant, thereby
preserving the enhanced hemodynamics resulting from the fusion
depolarization.