The present invention relates to an adhesive bandage with reduced pain during removal, whose flat strip substrate has a sticking front, a non-sticking back and four sides. And, both areas of said sticking front and non-sticking back are greater than those of four sides; The feature is: a strip of non-glued area is disposed between both of opposite parallel lengthwise lateral sides and two strips of glued area are parallel juxtaposed on both lengthwise sides of said non-glued area respectively on said sticking front, wherein a pair of glue-less indentations are formed on both end sides of said non-glued area but not adjacent said glued area of said strip substrate and being flush with both crosswise end sides; When the sticking front of the strip substrate sticks and presses on the skin epidermis around the wound, the middle non-glued area does not contact and stick on the skin epidermis S; Hence, when said adhesive bandage is to be ripped off upon changing medical dressing, our fingers can take anyone glue-less indentation on the strip substrate as grip fulcrum for lifting up to achieve the purpose of tearing off said strip substrate from the skin epidermis with effect of no painful feeling by such tearing off action.