A compound of Formula (I): ##STR00001## wherein: X is selected from the group consisting of O, S, and NR.sup.17, where R.sup.17 is hydrogen or lower alkyl; A and Y are CH, N, NR.sup.17, O, or S; C.sup.1 and C.sup.2 are each C or N, wherein C.sup.1 and C.sup.2 are the same or different; D.sup.1 and D.sup.2 are each C or N, wherein D.sup.1 and D.sup.2 are the same or different; B and Z are CH, N, or NR.sup.17, provided that B, Z, or both B and Z are not present when A, Y, or both A and Y are O, S, or NR.sup.17; R.sup.13, R.sup.14, R.sup.1 and R.sup.8 can be present or absent, and when present are selected from the group consisting of H, lower alkyl, halogen, alkoxyl, aryloxyl, aralkoxy and hydroxyl; R.sup.15 and Rare selected from the group consisting of H, lower alkyl, halogen, alkoxyl, aryloxyl, aralkoxy and hydroxyl; R.sup.3 and R.sup.6 are each independently selected from the group consisting of H, hydroxy, lower alkyl, cycloalkyl, aryl, aralkyl, alkoxyl, hydroxycycloalkyl, alkoxycycloalkyl, hydroxyalkyl, aminoalkyl, acyloxy, acetoxy, and alkylaminoalkyl; and R.sup.2, R.sup.4, R.sup.5 and R.sup.7 are each independently selected from the group consisting of H, lower alkyl, alkoxyalkyl, cycloalkyl, aryl, aralkyl, hydroxyalkyl, aminoalkyl, and alkylaminoalkyl, or R.sup.2 and R.sup.4 together or R.sup.5 and R.sup.7 together represent a C.sub.2 to C.sub.10 alkyl, hydroxyalkyl, or alkylene, or R.sup.3 and R.sup.4 together or R.sup.6 and R.sup.7 together are: ##STR00002## wherein n is a number from 1 to 3, and R.sup.9 is H or --CONHR.sup.10NR.sup.11R.sup.12, wherein R.sup.10 is lower alkyl and R.sup.11 and R.sup.12 are each independently selected from the group consisting of H and lower alkyl.