The present invention relates to novel triazolo-pyridines of the formula I
##STR00001## wherein R.sup.1 is fluoro;s is an integer from two to
three;R.sup.2 is (C.sub.3-C.sub.6)cycloalkyl optionally substituted by
one or two moieties independently selected from the group consisting of
halo, (C.sub.1-C.sub.4)alkyl, hydroxy, (C.sub.1-C.sub.6)alkoxy and
(C.sub.1-C.sub.6)alkyl-(C.dbd.O)--O--;or R.sup.2 is
(C.sub.1-C.sub.6)alkyl optionally substituted by one or two moieties
independently selected from the group consisting of halo,
(C.sub.1-C.sub.6)alkyl, hydroxy, (C.sub.1-C.sub.6)alkoxy and
(C.sub.1-C.sub.6)alkyl-(C.dbd.O)--O--;with the proviso that said compound
of formula I cannot
be6-[4-(2,4-Difluoro-phenyl)-oxazol-5-yl]-3-isopropyl-[1,2,4]triazolo[4,3-
-a]pyridine;
or6-[4-(3,4-Difluoro-phenyl)-oxazol-5-yl]-3-isopropyl-[1,2,4]triazolo[4,3-
-a]pyridine;to intermediates for their preparation, to pharmaceutical
compositions containing them and to their medicinal use. The compounds of
the present invention are potent inhibitors of MAP kinases, preferably
p38 kinase. They are useful in the treatment of inflammation,
osteoarthritis, rheumatoid arthritis, cancer, repurfusion or ischemia in
stroke or heart attack, autoimmune diseases and other disorders.