Adaptive battery conditioning employs battery chemistry determination to establish how, when and whether to condition a battery. As a result, the conditioning is optimized for the determined battery chemistry. Further, conditioning of a battery that is not conditionable, such as a nonrechargeable battery, is prevented. A device determines battery chemistry in situ from a measurement of a characteristic of an installed battery, and conditions the installed battery in situ. The device can be a battery-powered consumer electronic device or a battery charging and conditioning system that is independent of an electronic device that uses the conditioned battery. A method of adaptive battery conditioning includes determining a chemistry of a battery from a measurement of a battery characteristic, and conditioning the battery according to the determined battery chemistry.