The present invention relates to benzonaphthoazulene derivatives of tiophene class, to their pharmacologically acceptable salts and solvates, to processes and intermediates for the preparation thereof as well as to their antiinflammatory effects, especially to the inhibition of tumor necrosis factor-.alpha. (TNF-.alpha.) production and the inhibition of interleukin-1 (IL-1) production as well as to their analgetic action.