A mixing chamber probe adaptor comprising a chamber connector and a probe connector is provided. The mixing chamber probe adaptor imparts a fixed spatial joining of a chamber to a probe and allows a mixing chamber to be received by the chamber connector. In some embodiments, the mixing chamber probe adaptor will be adapted to connect to a spring-loaded probe and receive a micro mixing tee. In other embodiments, the mixing chamber probe adaptor may be used with other types of chambers and probes.