The present invention relates to a method for automation of software upgrade of network elements in data and communication networks. In a preferred embodiment of the present invention, an upgrade of network elements in a communication system is controlled from one certain workstation. Before the actual activation of the new software of the network elements takes place, the hardware configuration (5) is validated ensuring that the new software is loadable in the hardware. The software configuration is then also validated ensuring that the new software and the existing software are compatible. A health check is then executed investigating whether the status of the network elements is as required. Then, the certain workstation from which the upgrade is controlled is assigned exclusive network administration access to the network elements. Assuming that the above mentioned is carried through successfully, the actual activation of the new software is executed. Thereafter, the exclusive access which was assigned to the workstation is released, and before cleaning up and terminating, post validation and post health checks are executed.

 
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> Recombinant MHC molecules useful for manipulation of antigen-specific T-cells

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