An osteoporosis assessment system and method. The system and method generally include an input device that can be a computer that can be further connected to a network. The system can therefore be web-based. The system receives patient data and data related to osteoporosis. The method is implemented to correlate the patient data and the osteoporosis data and output is generated that personalizes the osteoporosis data to the patient based on the valued activities of the patient, so that the patient can understand his or her personal fracture risk assessment, therapy needs determination and therapy progress measurement. Therapy and treatment recommendations can also be generated.