A system, method, and computer program product are disclosed for prohibiting unauthorized access to a protected region of memory. A protected region of memory and a trusted region of memory are both specified. A call to access a location within the protected region of memory is received. An origination location of the call is then determined. In response to a determination that the origination location is within the trusted region, the call is permitted to access the protected region of memory. In response to a determination that the origination location is outside of the trusted region, the call is prohibited from accessing the protected region of memory.