The present invention relates to a composition for regulating the trophism of hair follicles and the cutaneous production of sebum and its use in androgenetic alopecia, comprising the synergic association of an extract from Boehmeria Nippononivea with a compound active at the keratin epithelial structure level, selected from specific sulfur-donor compounds and antioxidants. The composition of the invention is suitable for topical and/or oral administration.