The present invention relates to compounds of the general formula(Ig) or pharmaceutically acceptable salts thereof with an acid or a base, or pharmaceutically acceptable prodrugs or a stereoisomer thereof, wherein R.sup.1 independently represents H, alkyl, cycloalkyl, hydroxyalkyl, haloalkyl, haloalkyloxy, aryl, or heteroaryl; R.sup.2 independently represents NR.sup.3R.sup.5, R.sup.3 independently represents H, COR.sup.6, CO.sub.2R.sup.6, SOR.sup.6, SO.sub.2R.sup.6, SO.sub.3R.sup.6, alkyl, cycloalkyl, alkoxy, --NH.sub.2, alkylamine, --NR.sup.7COR.sup.6, halogen, --OH, --SH, alkylthio, hydroxyalkyl, haloalkyl, haloalkyloxy, aryl or heteroaryl; R.sup.5 independently represents H, COR.sup.6, CO.sub.2R.sup.6, SOR.sup.6, SO.sub.2R.sup.6, SO.sub.3R.sup.6, alkyl, cycloalkyl alkoxy, --NH.sub.2, alkylamine, --NR.sup.7COR.sup.6, halogen, --OH, --SH, alkylthio, hydroxyalkyl, haloalkyl, haloalkyloxy, aryl or heteroaryl; R.sup.6 independently represents H, alkyl, cycloalkyl, --NH.sub.2, alkylamine, aryl or heteroaryl; R.sup.7 independently represents H, alkyl, cycloalkyl, alkoxy, --OH, --SH, alkylthio, hydroxyalkyl, aryl, or heteroaryl; p is 0, or 1; q is 0, or 1; X is CO, CS, or SO.sub.2.