The present invention relates to novel compounds for the inhibition of
cyclin-dependent kinases, and more particularly, to chromenone
derivatives of formula (Ia), ##STR00001## wherein R.sub.1, R.sub.2,
R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and A have the meanings
indicated in the claims. The invention also relates to processes for the
preparation of the compounds of formula (Ia), to methods of inhibiting
cyclin-dependent kinases and of inhibiting cell proliferation, to the use
of the compounds of formula (Ia) in the treatment and prophylaxis of
diseases, which can be treated or prevented by the inhibition of
cyclin-dependent kinases such as cancer, to the use of the compounds of
formula (Ia) in the preparation of medicaments to be applied in such
diseases. The invention further relates to compositions containing a
compound of formula (Ia) either alone or in combination with another
active agent, in admixture or otherwise in association with an inert
carrier, in particular pharmaceutical compositions containing a compound
of formula (Ia) either alone or in combination with another active agent,
together with pharmaceutically acceptable carrier substances and
auxiliary substances.