In accordance with an embodiment of the invention, an integrated air processing device includes a housing defining an air inlet, an air outlet, and a pathway from the inlet to the outlet. An air decontamination section, an air conditioning section, and a heating section are provided along the pathway. A blower is also provided along the pathway, to drive air from the inlet to the outlet, along the pathway. In another example, an integrated air processing device includes a housing as above, and an air conditioning section and a heating section along the pathway. An air decontamination section and/or a blower may also be provided along the pathway. In accordance with another embodiment, a portable isolation containment system includes one or more portable containment enclosures coupled to the integrated air processing devices described above. Methods are disclosed, as well.