Disclosed is a printing plate material comprising a support and provided thereon, a hydrophilic layer and a thermosensitive image formation layer containing a blocked isocyanate compound, which is a reaction product of an isocyanate compound, a polyol, and an isocyanate group-blocking material, wherein the thermosensitive image formation layer is formed by coating on the support an aqueous thermosensitive image formation layer coating liquid containing the blocked isocyanate compound.