The present invention provides a compound of formula (I): ##STR00001##
or a pharmaceutically acceptable salt thereof. These compounds are
inhibitors of protein kinases, particularly inhibitors of PIM-1, CDK-2,
GSK-3, and SRC mammalian protein kinases. The invention also provides
pharmaceutically acceptable compositions comprising the compounds of the
invention and methods of utilizing those compounds and compositions in
the treatment of various protein kinase mediated disorders.