A game controller according to the present invention enables a user to perform exercises to control a gaming or virtual reality scenario. The game controller or exercise device includes an exercise structure and control circuitry. The exercise structure enables a user seated on a rotatable support member to apply forces to rotate the support member and user body. The rotation of the user on the exercise structure is measured and utilized to control the game scenario.

 
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> COMPOSITIONS CAPABLE OF FACILITATING PENETRATION ACROSS A BIOLOGICAL BARRIER

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