A nucleic acid molecule or construct alone or with a promoter suitable for
expression control is contemplated that codes for a HLH2 haemocyanin
polypeptide and comprises at least one intron sequence, as well as
haemocyanin fusion proteins. The construct further can comprise a nucleic
acid sequence that codes for an antigen. Host cells are also contemplated
that contain the nucleic acid molecules or construct and recombinant
expression product thereof. The invention further relates to a
pharmaceutical composition that comprises the expression product of that
nucleic acid and antibodies obtainable by immunization of an animal
therewith, as well as use of the antibodies in screening methods for the
identification of tumors.